Consumer Research Study 1 – Test Market Group

Evaluating lactoferrin as a dietary supplement for the support of a healthy complexion.

44 participants, for whom other so called ‘acne cures’ had proven ineffective, but who shared the desire to be acne-free, were enrolled in the study (223 males and 21 females).

For 8 weeks the subjects were supplemented with 200mg lactoferrin. Photographs taken by an independent photographer were blinden and evaluated by an independent dermatologist.

Subject data were collected at week 0 (baseline), which occurred before supplementation started, as well as at weeks 2, 4 and 8.

The number of blackheads (open comedones) and non-blackheads (including whiteheads, closed comedones, papules, pustules and nodulocystic lesions) were counted on the forehead, left cheek, right cheek, chin and nose. For each subject, blackheads and non-blackheads were summed over the facial regions each week.

• After stopping lactoferrin supplementation at week 8, the number of blemishes started to increase as measured by an increased number of blemishes at week 12.

• Over 76% of the participants observed visible improvements, including fewer blemishes, a reduction in the amount of redness and less oiliness.

Consumer Research Study 2 – Test Market Group

Evaluating the effectiveness of lactoferrin in a dietary supplement regimen.

42 participants were enrolled in the study and divided into 3 groups. The groups were stratified for gender and baseline acne severity. All groups were supplemented with Lactoferrin for 7 successive weeks. Group 1 received a total amount of 25mg lactoferrin per day; Group 2 received a total amount of 100mg lactoferrin per day; Group 3 received a total amount of 200mg lactoferrin per day.

Subjects had front profile photographs taken by an independent photographer. Photographs were blinded and evaluated by a dermatologist. Subject data were reported at week 0 (baseline) and week 8.

Clinical Research Study – Effectiveness On Ethnic Skin Types

Evaluating the effectiveness of lactoferrin on ethnic skin types.

This study focussed on 14 subjects aged 15-27 years old (4 male and 10 female) with mild to moderate acne.

For 12 weeks subjects were supplemented with 200mg lactoferrin. Examination photographs were taken by an independent photographer at weeks 0, 2, 4, 8 and 12. Photographs were then blinded and evaluated by an independent dermatologist.

The number of blackheads (open comedones) and non-blackheads (including whiteheads, closed comedones, papules, pustules and nodulocystic lesions) were counted on the forehead, left cheek, right cheek, chin and nose. For each subject, blackheads and non-blackheads were summed over the facial regions each week.

Additionally, participants were interviewed on self-assessment of acne, complexion, self esteem and confidence.

• Lactoferrin supplementation was observed to be effective on both Asian and Caucasian skin types, with a median reduction in blemishes of 29% by week 2 and 74% by week 12.
• Greater effect was observed on infected and inflamed lesions and a marked reduction in skin redness was observed.
• Participants interviewed rated the effectiveness of treatment from fair to very good in 75% of cases and participants reported a reduced number of lesions, less inflammation, a reduction in redness, healing time accelerated by an average of 3-4 days.
• No adverse effects were reported during interviews. Some subjects noted a slight whitening effect of the skin.