How Does PRAVENAC help: clear skin™ Work?
PRAVENAC help: clear skin™ is a nutritional supplement formulation with antimicrobial, anti-inflammatory and antioxidant properties derived from the active ingredients; lactoferrin, high extract aloe vera and zinc gluconate.
These properties help PRAVENAC help: clear skin™ target the symptoms of acne, reduce the appearance of redness and blemishes and reduce the impact of acne related scarring – without time consuming bathroom routines, prescription medicines and expensive trips to the dermatologist.
The active ingredients in our formulation include Lactoferrin, a protein found naturally in milk from humans and cows. Research has suggested that Lactoferrin may help protect the body from pathogenic microorganisms such as bacterial, viral and fungal infections by stimulating the immune system, promoting healthy bacteria in the gut and regulating iron metabolism.
Find out more about how PRAVENAC help: clear skin™ works by clicking on the sections below:
Cutibacterium acnes, or C. acnes for short, is a relatively slow growing bacteria linked to the symptoms of acne (and formerly known as propionibacterium).
Cutibacterium acnes survives on human skin by feeding on fatty acids in sebum, an oily substance secreted by the sebaceous glands found in hair follicles on human skin. This bacterium is part of the flora present on the majority of people’s skin, neither being of benefit or causing harm in normal conditions.
However, increased sebum production or blockage of pores (including the formation of whiteheads and blackheads) can result in C. acnes bacteria multiplying beyond normal levels. When this happens, the digestive enzymes produced by this bacterium can destabilise the layers of cells which form the walls of the follicle – and this damage, in combination with debris and irritants produced by the accelerated growth of C. acnes, can trigger inflammation resulting in spots and blemishes.
As the damage caused by C. acnes increases, pores can become more susceptible to infection from other microbes such as Staphylococcus aureus – resulting in a worsening of symptoms including the appearance of papules (small red, tender bumps), pustules (papules with pus at their tips), nodules (large painful lumps beneath the surface of the skin) and cystic lesions (painful, pus filled lumps beneath the surface of the skin) – known more commonly as cystic acne.
The lactoferrin in PRAVENAC help: clear skin™ helps inhibit the growth of C. acnes by binding with the iron molecules which these bacterium would normally use, making it harder for the C. acnes to flourish and for the symptoms of acne to persist.
Lactoferrin is a glycoprotein present naturally in exocrine secretions: milk, tears, nasal exudate, bronchial mucus, gastrointestinal fluids and saliva. PRAVENAC help: clear skin™ comprises a specific and exceptionally high grade of lactoferrin from which pathogenic lipopolysaccharides (which can cause an immune response in the body) have been removed. Further, the majority of any available binding iron has been removed from the material – which in turn has the effect of increasing the molecular performance of the lactoferrin against C. acnes bacteria.
As the number of C. acnes and Staphylococcus aureus microbes increases, so do the levels of digestive enzymes produced by these bacteria.
These digestive enzymes combined with a build up of microbial debris and compounds known to irritate the skin. The causes further damage to skin cells and triggers your body’s immune system response.
Inflammation is a normal part of the body’s protective response against injury and infection. It is a complex process which includes different types of immune cells, clotting proteins and signaling molecules as well as an increase in blood flow to the affected area – the cause of the redness and heat often experienced by this response.
Many topical treatments which address the symptoms of acne rely on high concentrations of anti-inflammatory compounds such as benzoyl peroxide and retinoids to treat symptoms of acne through application to the skin.
PRAVENAC help: clear skin™ takes a different approach, with the three main ingredients in our food supplement contributing to the reduction of inflammation. By reducing inflammation, in combination with reducing the proliferation of C. acnes bacteria, the appearance of spots and blemishes is diminished.
PRAVENAC help: clear skin™ includes a particularly high quality Aloe Vera extract along with Zinc Gluconate, a highly bioavailable form of zinc known to contribute to the maintenance of normal skin and normal function of the immune system.
Oxidative stress is a state in which the cells of the body are subject to damage caused by a buildup of harmful peroxides and free radicals.
This damage can affect proteins, lipids and DNA within cells and interfere with normal cellular functions.
Oxidative stress may play a role in contributing to the onset of teenage and adult acne, along with hormone, diet and lifestyle factors. A number of studies have observed an increase in oxidative stress and reduction in available antioxidants in those suffering with acne. Antioxidants play an important role in reducing oxidative stress, by neutralising free radicals and reducing peroxide levels.
PRAVENAC help: clear skin™ is rich in antioxidants including lactoferrin and polyphenols from high extract aloe vera. The zinc gluconate in PRAVENAC help: clear skin™ is known to play a role in the process of cell division and normal DNA synthesis and contributes to the protection of cells from oxidative stress.